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Peptide record

TPDB91911

KT2 Antibacterial Anticancer Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB91911
KT2
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia CancerPPD 2.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
NGVQPKYKWWKWWKKWW-NH2
Physicochemical Analysis
C126H164N30O21
ARDCEHILMFST
W
2434.88
10.77
5
0
8
+5
-5.56
-1.824
17.06
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
34490
1416.50
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
0
L
5
K
0
M
0
F
1
P
0
S
0
T
6
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 1 S: 0 T: 0 W: 6 Y: 1 V: 1
Chemical Descriptors
17
C126H164N30O21
2434.88
10.77
+5
-5.56
-1.824
Amidation
L
Linear
Free
Antimicrobial and Anticancer Antimicrobial
Crocodylus siamensis
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 53.41 ± 1.0 µM
Anticancer
53.41

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

Sulforhodamine B assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2016

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 30.81 ± 0.2 µM
Anticancer
30.81

Target

Cervical Cancer
CaSki
Cervix

Assay & Model

Sulforhodamine B assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2016
Evidence 3 Activity

Activity

IC50
IC50 = 90.25 µg/mL
Anticancer
90.25 µg/mL

Target

Colon Cancer
HCT-116
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2018