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Peptide record

TPDB91898

Frenatin 2.2S Antibacterial Anticancer Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB91898
Frenatin 2.2S
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 SATPdb dbACP Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: alpha-amidation
Sequence
GLVGTLLGHIGKAILS
Physicochemical Analysis
C71H125N19O19
RNDCEQMFPWY
GL
1548.89
10.10
2
0
8
+1
-0.70
1.250
170.62
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
1
H
2
I
4
L
1
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 1 I: 2 L: 4 K: 1 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
16
C71H125N19O19
1548.89
10.10
+1
-0.70
1.250
alpha-amidation
L
Linear
Free
Antimicrobial
Sphaenorhynchus lacteus
Evidence Records 1 records
Evidence 1 Activity

Activity

LC50
LC50 = 75 ± 5 µM
Anticancer
75

Target

Lung Cancer
A-549
Lung

Assay & Model

Trypan blue assay
24-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2014

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.