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Peptide record

TPDB91896

N-3L Antibacterial Anticancer Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB91896
N-3L
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP dbAMP 3.0 iACP-DRLF HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KWFKKIPKFLHLLKKF-NH2
Physicochemical Analysis
C109H169N25O17
ARNDCEQGMSTYV
K
2101.70
11.21
7
0
8
+6
0.12
-0.300
97.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
261.69
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
3
L
6
K
0
M
3
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 3 K: 6 M: 0 F: 3 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C109H169N25O17
2101.70
11.21
+6
0.12
-0.300
Amidation
L
Linear
Free
Antibacterial
Ceropin A
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50=4 µM
Anticancer
4 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT/MTS assay
48-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2001

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.
Evidence 2 Activity

Activity

IC50
IC50=4.2 µM
Anticancer
4.2 µM

Target

Leukemia Cancer
K-562
Blood

Assay & Model

MTT/MTS assay
48-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2001