Back to search

Peptide record

TPDB91798

Chaxapeptin Antibacterial Anticancer Antifungal standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB91798
Chaxapeptin
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 dbACP iACP-DRLF Antifungipept
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
N-terminal: Cyclized to form macrolactam ring
Sequence
GFGSKPLDSFGLNFF
Physicochemical Analysis
C79H109N17O21
ARCEQHIMTWYV
F
1632.84
6.75
1
1
6
-0
-2.26
0.233
52.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
1
D
0
C
0
E
0
Q
3
G
0
H
0
I
2
L
1
K
0
M
4
F
1
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 2 K: 1 M: 0 F: 4 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C79H109N17O21
1632.84
6.75
-0
-2.26
0.233
Free
L
Mix
Cyclized to form macrolactam ring
Antimicrobial and Anticancer
Streptomyces leeuwenhoekii Strain C58
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell invasion
Cell invasion < 50% at 50 µM
Anticancer
<50 % at 50 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

CyQUANT Direct assay
36-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.