Peptide record

TPDB91780

[T5k]temporin-DRa (Frogs, amphibians, animals) Temporin-1DRa [T5k] Antimicrobial Antibacterial modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB91780
[T5k]temporin-DRa (Frogs, amphibians, animals) Temporin-1DRa [T5k]
Antimicrobial Antibacterial
Anti-infective peptides
DBAASP DRAMP
modified_plain
Yes
A 14-aa modified multi-activity (Antimicrobial and Antibacterial) peptide sequence curated from DBAASP and DRAMP, with an available 3D structural model.
C-terminal: Amidation
Sequence
HFLGKLVNLAKKIL-NH2
Physicochemical Analysis
C77H132N20O16
RDCEQMPSTWY
L
1594.02
10.84
4
0
8
+3
0.58
0.693
167.14
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
4
L
3
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 4 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
14
C77H132N20O16
1594.02
10.84
+3
0.58
0.693
AMD Amidation
Free
Evidence Records 1 records
Evidence 1 Activity

Target

Cutibacterium acnes

Source & Reference

DRAMP DBAASP
Popovic S, Urbán E, Lukic M, Conlon JM.
Peptides with antimicrobial and anti-inflammatory activities that have therapeutic potential for treatment of acne vulgaris.
Peptides. 2012 Apr 34(2):275-282.

Other

Source Activity Label Source Definition
Antimicrobial Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Rana draytonii
Comment: No comments found on DRAMP database