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Peptide record

TPDB91775

LFcin17–30 Antibacterial Anticancer Antifungal Cell-penetrating Peptides Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB91775
LFcin17–30
Antibacterial Anticancer Antifungal Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP pep-lab Peptipedia CancerPPD 2.0 Antifungipept CAFPdb CPPsite3.0 HemoPI PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, pep-lab, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
FKCRRWQWRMKKLG-NH2
Physicochemical Analysis
C88H139N29O16S2
ANDEHIPSTYV
RK
1923.38
12.14
6
0
5
+6
0.13
-1.421
27.86
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
571.91
2
Residue Composition
number
0
A
3
R
0
N
0
D
1
C
0
E
1
Q
1
G
0
H
0
I
1
L
3
K
1
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 3 M: 1 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
14
C88H139N29O16S2
1923.38
12.14
+6
0.13
-1.421
Amidation
L
Linear
Free
Antimicrobial
Lectoferrin Peptide
Evidence Records 2 records
Evidence 1 Activity

Activity

cell viability
cell viability ~ 50% at 1 µM
Anticancer
~50 % at 1 µM

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
12-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

cell viability
cell viability ~ 70% at 20 µM
Anticancer
~70 % at 20 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
6-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023