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Peptide record

TPDB91774

KLA (CPP94) Antibacterial Anticancer Antifungal Antiparasitic Antiviral Cell-penetrating Peptides Hemolysis Toxicity Tumor-homing Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB91774
KLA (CPP94)
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Cell-penetrating Peptides Hemolysis Toxicity Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept CAFPdb dbAMP CPPsite3.0 PerseuCPP APD_complete PD_Hemolysis TumorHoPe2.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
C-terminal: Conjugated with TAMRA
Sequence
KLAKLAKKLAKLAK
Physicochemical Analysis
C72H138N20O15
RNDCEQGHIMFPSTWYV
K
1524.01
11.21
6
0
8
+6
3.02
-0.071
140.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C72H138N20O15
1524.01
11.21
+6
3.02
-0.071
Conjugated with TAMRA
L
Linear
Free
N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli Dh5Α

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
TAMRA dye
Cytoplasm
Penetration efficiency- 220.038625A.U.
In vitro
CCSSTTSCC
Additional Detail Fields 1 fields
CCSSTTSCC