Back to search

Peptide record

TPDB91764

Tritrp-Lys Antibacterial Anticancer Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB91764
Tritrp-Lys
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
VKKFPWWWPFLKK-NH2
Physicochemical Analysis
C96H132N20O14
ARNDCEQGHIMSTY
K
1790.23
11.00
4
0
7
+4
-3.44
-0.608
52.31
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
16500
921.67
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
4
K
0
M
2
F
2
P
0
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 4 M: 0 F: 2 P: 2 S: 0 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
13
C96H132N20O14
1790.23
11.00
+4
-3.44
-0.608
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 11.5 µM
Anticancer
11.5 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.