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Peptide record

TPDB91762

Temporin-CPa Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91762
Temporin-CPa
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia CancerPPD 2.0 AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
IPPFIKKVLTTVF-NH2
Physicochemical Analysis
C76H123N15O16
ARNDCEQGHMSWY
IKFPTV
1502.90
10.60
2
0
7
+2
-0.14
1.108
134.62
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
2
K
0
M
2
F
2
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 2 M: 0 F: 2 P: 2 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
13
C76H123N15O16
1502.90
10.60
+2
-0.14
1.108
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

LC50
LC50 = 80 µM
Anticancer
80 µM

Target

Breast Cancer
4T1
Breast

Assay & Model

MTS assay
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.