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Peptide record

TPDB91760

Temporin-1Oc Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91760
Temporin-1Oc
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 dbACP iACP-DRLF AFP-GFuse Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
FLPLLASLFSRLF-NH2
Physicochemical Analysis
C77H118N16O16
NDCEQGHIKMTWYV
L
1523.88
11.05
1
0
9
+1
-4.84
1.654
157.69
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
0
K
0
M
3
F
1
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 0 M: 0 F: 3 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C77H118N16O16
1523.88
11.05
+1
-4.84
1.654
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 2 records
Evidence 1 Activity

Activity

LC50
LC50 = 65 µM
Anticancer
65 µM

Target

Breast Cancer
4T1
Breast

Assay & Model

MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

LC50
LC50 = 50 µM
Anticancer
50 µM

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018