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Peptide record

TPDB91715

S4(13) Antibacterial Antifungal Antiparasitic Cell-penetrating Peptides Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91715
S4(13)
Antibacterial Antifungal Antiparasitic Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb dbAMP 3.0 CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with rhodamine B
Sequence
ALWKTLLKKVLKA-NH2
Physicochemical Analysis
C74H130N18O15
RNDCEQGHIMFPSY
LK
1511.96
11.00
4
0
8
+4
-0.26
0.446
157.69
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
363.77
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
4
K
0
M
0
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C74H130N18O15
1511.96
11.00
+4
-0.26
0.446
Amidation
L
Antimicrobial
Linear
Conjugation with rhodamine B
N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3
US 20040132970

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Antimicrobial
Protein derived
Fluorophore (rhodamine)
Cytoplasm
Non-endocytic mechanism
In vitro
CTHHHHHHHHTTC
Additional Detail Fields 1 fields
CTHHHHHHHHTTC