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Peptide record

TPDB91710

L-K6 Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91710
L-K6
Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CancerPPD 2.0 Antifungipept CAFPdb dbAMP CPPsite3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
IKKILSKIKKLLK-NH2
Physicochemical Analysis
C75H145N19O15
ARNDCEQGHMFPTWYV
K
1553.09
11.21
6
0
6
+6
3.46
0.054
180.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
3
L
6
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 3 K: 6 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C75H145N19O15
1553.09
11.21
+6
3.46
0.054
Amidation
L
Linear
Free
Antimicrobial and Anticancer
Temporin 1CEb analogue
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 31 µM
Anticancer
31 µM

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.