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Peptide record

TPDB91707

Tritrp-W678F Antibacterial Anticancer Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91707
Tritrp-W678F
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia CancerPPD 2.0 Antifungipept CAFPdb
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
VRRFPFFFPFLRR-NH2
Physicochemical Analysis
C90H129N25O14
ANDCEQGHIKMSTWY
F
1785.17
12.88
4
0
7
+4
-2.00
0.062
52.31
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
5
F
2
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 5 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C90H129N25O14
1785.17
12.88
+4
-2.00
0.062
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 24.6 µM
Anticancer
24.6 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.