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Peptide record

TPDB91704

Indolicidin-Lys Antibacterial Anticancer Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91704
Indolicidin-Lys
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
ILPWKWPWWPWKK-NH2
Physicochemical Analysis
C100H131N21O14
ARNDCEQGHMFSTYV
W
1851.27
10.84
3
0
7
+3
-5.80
-0.977
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
27500
1485.46
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
3
K
0
M
0
F
3
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 3 M: 0 F: 0 P: 3 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
13
C100H131N21O14
1851.27
10.84
+3
-5.80
-0.977
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 9.5 µM
Anticancer
9.5 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.