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Peptide record

TPDB91703

PuroA-Arg Antibacterial Anticancer Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91703
PuroA-Arg
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
FPVTWKWWKWWKG-NH2
Physicochemical Analysis
C98H123N21O15
ARNDCEQHILMSY
W
1835.19
10.84
3
0
7
+3
-6.74
-0.915
22.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
27500
1498.49
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
3
K
0
M
1
F
1
P
0
S
1
T
5
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 3 M: 0 F: 1 P: 1 S: 0 T: 1 W: 5 Y: 0 V: 1
Chemical Descriptors
13
C98H123N21O15
1835.19
10.84
+3
-6.74
-0.915
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 10.0 µM
Anticancer
10.0 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.