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Peptide record

TPDB91696

Tylotoin Antibacterial Anticancer Cell-penetrating Peptides Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB91696
Tylotoin
Antibacterial Anticancer Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugated with CF
Sequence
KCVRQNNKRVCK-NH2
Physicochemical Analysis
C59H110N24O16S2
ADEGHILMFPSTWY
K
1475.79
10.82
5
0
2
+5
5.67
-1.483
48.33
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
125
8.47
5
Residue Composition
number
0
A
2
R
2
N
0
D
2
C
0
E
1
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 2 D: 0 C: 2 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
12
C59H110N24O16S2
1475.79
10.82
+5
5.67
-1.483
Amidation
L
Linear
Conjugated with CF
N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HaCaT And HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
CF dye
Cytoplasmic vesicles
Lower extent of internalization in HaCat cells
In vitro
CCCCCEETTEEC
Additional Detail Fields 1 fields
CCCCCEETTEEC