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Peptide record

TPDB91691

L12 Antibacterial Anticancer Antihypertensive Antiviral Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB91691
L12
Antibacterial Anticancer Antihypertensive Antiviral Cell-penetrating Peptides
Anti-infective peptides Cardiometabolic peptides Cancer-related peptides Delivery and barrier-penetrating peptides
AntiBP3 pep-lab Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF AI4AVP CPPsite3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antihypertensive, and other sources) peptide sequence curated from AntiBP3, pep-lab, Peptipedia, and other sources, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
FKCRRWQWRMKK
Physicochemical Analysis
C80H125N27O14S2
ANDEGHILPSTYV
RK
1753.17
12.14
6
0
4
+6
0.68
-1.942
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
627.44
2
Residue Composition
number
0
A
3
R
0
N
0
D
1
C
0
E
1
Q
0
G
0
H
0
I
0
L
3
K
1
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 3 M: 1 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
12
C80H125N27O14S2
1753.17
12.14
+6
0.68
-1.942
Free
L
Linear
Conjugated with FITC
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A549 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC dye
L12-FITC were internalized at low concentrations (< 1μM)
In vitro
CCCCCCCCSSCC
Additional Detail Fields 1 fields
CCCCCCCCSSCC