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Peptide record

TPDB91686

IDR-1080 Antibacterial Antiparasitic Cell-penetrating Peptides Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB91686
IDR-1080
Antibacterial Antiparasitic Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia i2APP CPPsite3.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antiparasitic, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, i2APP, and other sources, with an available 3D structural model.
N-terminal: Primaquine Conjugated
Sequence
VRLIVAVRIWRR
Physicochemical Analysis
C71H125N25O13
NDCEQGHKMFPSTY
R
1536.93
12.88
4
0
8
+4
0.25
0.692
178.33
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
357.86
0
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
12
C71H125N25O13
1536.93
12.88
+4
0.25
0.692
Free
L
Linear
Primaquine Conjugated
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Plasmodium Berghei

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Primaquine (PQ)
Conjugates were more active than the parent peptides
In vitro