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Peptide record

TPDB91553

HM11R Antibacterial Anticancer Blood-Brain Barrier Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB91553
HM11R
Antibacterial Anticancer Blood-Brain Barrier Cell-penetrating Peptides
Anti-infective peptides Cancer-related peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia dbACP B3Pred BBPpredict CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Blood-Brain Barrier, and other sources) peptide sequence curated from AntiBP3, Peptipedia, dbACP, and other sources, with an available 3D structural model.
N-terminal: Conjugation with His-Tag-Ar(40 Aa)-Nls
Sequence
RRRRRRRRRRR
Physicochemical Analysis
C66H134N44O12
ANDCEQGHILKMFPSTWYV
R
1736.08
13.40
11
0
0
+11
8.91
-4.500
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
11
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 11 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C66H134N44O12
1736.08
13.40
+11
8.91
-4.500
Free
L
Cationic
Linear
Conjugation with His-Tag-Ar(40 Aa)-Nls
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Assay & Model

Animals (male and female Slc:Wister rats, female NC/Nga slc mice and female DA/Slc rats)
Animals (male and female Slc:Wister rats, female NC/Nga slc mice and female DA/Slc rats)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
MTI-II(small nuclear acidic region)
Cytoplasm and Nuclei
In vitro and in vivo
CCCGGGGCCCC
Additional Detail Fields 1 fields
CCCGGGGCCCC