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Peptide record

TPDB91539

A4W-GGN5 Antibacterial Anticancer Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB91539
A4W-GGN5
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
FLGWLFKVASK-NH2
Physicochemical Analysis
C66H98N14O13
RNDCEQHIMPTY
LKF
1295.59
10.60
2
0
7
+2
-3.21
0.845
106.36
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
424.52
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
2
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 2 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
11
C66H98N14O13
1295.59
10.60
+2
-3.21
0.845
Amidation
L
Linear
Free
Anticancer
Gaegurin 5
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
EC50 = 98.63 ± 1.17 µM
Anticancer
98.63

Target

Colorectal Cancer
SW-480
Colon

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 = 22.07 ± 1.63 µM
Anticancer
22.07

Target

Colorectal Cancer
SW-620
Colon

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021