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Peptide record

TPDB91536

CM11 Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB91536
CM11
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 Antifungipept CAFPdb pep-lab dbAMP dbAMP 3.0 i2APP HemoPI PD_Hemolysis
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
WKLFKKILKVL-NH2
Physicochemical Analysis
C73H122N16O12
ARNDCEQGHMPSTY
K
1415.87
11.00
4
0
7
+4
-0.94
0.582
168.18
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
388.45
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
4
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
11
C73H122N16O12
1415.87
11.00
+4
-0.94
0.582
Amidation
L
Linear
Free
Antimicrobial
Cecropin-Melittin Hybrid Peptide
Evidence Records 2 records
Evidence 1 Activity

Activity

Survival rate
Survival rate = 47% at 32 µg/ml
Anticancer

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.
Evidence 2 Activity

Activity

Survival rate
Survival rate = 51% at 32 µg/ml
Anticancer

Target

Blood Cancer
Raji
Blood

Assay & Model

MTT assay
24-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0
CancerPPD2
2023