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Peptide record

TPDB91523

CyLoP-1 Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB91523
CyLoP-1
Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CAFPdb dbAMP CellPPD CellPPD-MOD CPPsite3.0 ToxinPred 3.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
N-terminal: Conjugation with K-FITC
Sequence
CRWRWKCCKK
Physicochemical Analysis
C61H97N21O11S3
ANDEQGHILMFPSTYV
CK
1396.76
10.32
5
0
2
+5
0.17
-1.500
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
11125
796.49
3
Residue Composition
number
0
A
2
R
0
N
0
D
3
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
10
C61H97N21O11S3
1396.76
10.32
+5
0.17
-1.500
Free
L
Cystein rich
Linear
Conjugation with K-FITC
N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

NIH-3T3, CCL-11, C6 glioma cells and PANC-1

Source & Reference

CPPsite3.0
CPPsite3
US20110027300

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cystein rich
Protein derived
Fluorophore (FITC)
Cytosol
High (greater than Tat, penetratin and R8)
Receptor mediated endocytosis
In vitro
CCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCC