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Peptide record

TPDB91520

CyLoP-1 Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB91520
CyLoP-1
Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CAFPdb dbAMP CellPPD CellPPD-MOD CPPsite3.0 ToxinPred 3.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Chemical: His-tag
Sequence
CRWRWKCCKK
Physicochemical Analysis
C61H97N21O11S3
ANDEQGHILMFPSTYV
CK
1396.76
10.32
5
0
2
+5
0.17
-1.500
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
11125
796.49
3
Residue Composition
number
0
A
2
R
0
N
0
D
3
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
10
C61H97N21O11S3
1396.76
10.32
+5
0.17
-1.500
Free
His-tag
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek-293T Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
rNef-Vif-Gp160-P24 and rNef-Vpu-Gp160-P24 polyepitope peptides
CyLoP-1 could efficiently transfer rNef-Vif-Gp160-P24 and rNef-Vpu-Gp160-P24 polyepitope peptides into the cells.
In vitro
CHHHHHHHTSCCCCCCC
Additional Detail Fields 1 fields
CHHHHHHHTSCCCCCCC