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Peptide record

TPDB91365

Turgencin B Antibacterial Anticancer Antifungal Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB91365
Turgencin B
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 DRAMP Peptipedia CancerPPD 2.0 dbACP Antifungipept ToxinPred 3.0
standard
No
A 35-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GIKEMLCNMACAQTVCKKSGGPLCDTCQAACKALG-NH2
Physicochemical Analysis
C143H248N42O46S8
RHFWY
C
3548.28
8.02
4
2
12
+2
5.02
0.269
67.14
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
375
10.57
12
Residue Composition
number
5
A
0
R
1
N
1
D
6
C
1
E
2
Q
4
G
0
H
1
I
3
L
4
K
2
M
0
F
1
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 1 C: 6 E: 1 Q: 2 G: 4 H: 0 I: 1 L: 3 K: 4 M: 2 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
35
C143H248N42O46S8
3548.28
8.02
+2
5.02
0.269
Amidation
L
Cyclic(C7-C31,C11-C27,C16-C24)
Free
Antimicrobial and Anticancer
Synoicum turgens
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 4.1 µM
Anticancer
4.1 µM

Target

Skin Cancer
A-2058
Skin

Assay & Model

Cell Viability assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.