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Peptide record

TPDB91363

Polybia-MP1 Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB91363
Polybia-MP1
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF AFP-GFuse Antifungipept CAFPdb i2APP ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
IDWKKLLDAAKQIL-NH2
Physicochemical Analysis
C78H131N19O20
RNCEGHMFPSTYV
LK
1655.01
9.76
3
2
8
+1
1.52
0.064
153.57
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
332.32
1
Residue Composition
number
2
A
0
R
0
N
2
D
0
C
0
E
1
Q
0
G
0
H
2
I
3
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 3 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C78H131N19O20
1655.01
9.76
+1
1.52
0.064
Amidation
L
Linear
Free
Antimicrobial
Polybia paulista
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 12.5 µM
Anticancer
12.5 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.