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Peptide record

TPDB91358

Turgencin A Antibacterial Anticancer Antifungal standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB91358
Turgencin A
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 DRAMP Peptipedia CancerPPD 2.0 dbACP Antifungipept
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GPKTKAACKMACKLATCGKKPGGWKCKLCELGCDAV-NH2
Physicochemical Analysis
C157H269N45O43S7
RNQHIFSY
K
3699.56
9.23
8
2
11
+6
6.42
-0.117
54.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
158.80
8
Residue Composition
number
5
A
0
R
0
N
1
D
6
C
1
E
0
Q
5
G
0
H
0
I
3
L
8
K
1
M
0
F
2
P
0
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 1 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 0 L: 3 K: 8 M: 1 F: 0 P: 2 S: 0 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
36
C157H269N45O43S7
3699.56
9.23
+6
6.42
-0.117
Amidation
L
Cyclic(C8-C33,C12-C29,C17-C26)
Free
Antimicrobial and Anticancer
Synoicum turgens
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 1.4 µM
Anticancer
1.4 µM

Target

Skin Cancer
A-2058
Skin

Assay & Model

Cell Viability assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.