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Peptide record

TPDB91323

Buforin2 Antibacterial Anticancer Antifungal Antiparasitic Antiviral Cell-penetrating Peptides Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB91323
Buforin2
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF Antifungipept CAFPdb AI4AVP AVPpred-BWR dbAMP 3.0 DRAVP 2.0 CellPPD-MOD CPPsite3.0 PerseuCPP ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
TRSSRAGLQFPVGRVHRLLRK-NH2
Physicochemical Analysis
C106H184N40O26
NDCEIMWY
R
2434.88
13.00
7
0
7
+6
4.61
-0.638
88.10
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
1
Q
2
G
1
H
0
I
3
L
1
K
0
M
1
F
1
P
2
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 3 K: 1 M: 0 F: 1 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
21
C106H184N40O26
2434.88
13.00
+6
4.61
-0.638
Amidation
L
Linear
Free
Antimicrobial
Bufo Bufo Gargarizans
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Cytotoxicity at 0.5 µg/ml
Anticancer

Target

Lymphoma Cancer
U-937
Blood

Assay & Model

MTT/MTS assay
6-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1996

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.