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Peptide record

TPDB91305

(LLKK)4 linear peptide Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB91305
(LLKK)4 linear peptide
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
LLKKLLKKLLKKLLKK-NH2
Physicochemical Analysis
C96H186N24O17
ARNDCEQGHIMFPSTWYV
LK
1948.68
11.36
8
0
8
+8
3.44
-0.050
195.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
8
L
8
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 8 K: 8 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C96H186N24O17
1948.68
11.36
+8
3.44
-0.050
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 4 records
Evidence 1 Activity

Activity

Cell Viability (%) ~ 14.1 ± 0.8 at 30 µg/mL
Anticancer

Target

Liver Cancer
SK-HEP-1
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Cell Viability (%) ~ 10.73 ± 2.4 at 30 µg/mL
Anticancer

Target

Colon Cancer
HCT-116
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
Evidence 3 Activity

Activity

Cell Viability (%) ~ 15.07 ± 0.5 at 30 µg/mL
Anticancer

Target

Breast Cancer
Bcap-37
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020
Evidence 4 Activity

Activity

Cell Viability (%) ~ 17.1 ± 5.0 at 30 µg/mL
Anticancer

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020