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Peptide record

TPDB91299

Crot(1-9,38-42) Antibacterial Anticancer Cell-penetrating Peptides Toxicity Tumor-homing Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB91299
Crot(1-9,38-42)
Antibacterial Anticancer Cell-penetrating Peptides Toxicity Tumor-homing Peptides
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP TumorHoPe2.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CellPPD, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugated with 5(6)-Carboxyfluorescein (CF)
Sequence
YKQCHKKGGKKGSG-NH2
Physicochemical Analysis
C64H108N22O18S1
ARNDEILMFPTWV
K
1505.76
10.48
6
0
1
+5
5.48
-1.957
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
98.95
4
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
1
Q
4
G
1
H
0
I
0
L
5
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 4 H: 1 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C64H108N22O18S1
1505.76
10.48
+5
5.48
-1.957
Amidation
L
Cationic and amphiphilic
Linear
Conjugated with 5(6)-Carboxyfluorescein (CF)
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Monomac-6, Ebc-1 And Calu-1 Cells Mycobacterium Tuberculosis H37Rv

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic and amphiphilic
Synthetic
CF dye and Isoniazid (INH) at N terminus
In vitro
CCSCSSCCSCCCC
Additional Detail Fields 1 fields
CCSCSSCCSCCCC