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Peptide record

TPDB91289

PST13-RK Antibacterial Anticancer Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91289
PST13-RK
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KKKFPWWWPFKKK-NH2
Physicochemical Analysis
C97H136N22O14
ARNDCEQGHILMSTYV
K
1834.29
11.21
6
0
5
+6
-0.97
-1.823
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
899.53
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
6
K
0
M
2
F
2
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 6 M: 0 F: 2 P: 2 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
13
C97H136N22O14
1834.29
11.21
+6
-0.97
-1.823
Amidation
L
Linear
Free
Antimicrobial
Derivative of tritrpticin
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 =90 µg/ml
Anticancer
90 µg/mL

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT/MTS assay

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 =80 µg/ml
Anticancer
80 µg/mL

Target

Breast Cancer
MDA-MB-361
Breast

Assay & Model

MTT/MTS assay

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008