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Peptide record

TPDB91287

SB-37 Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB91287
SB-37
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb iACP-DRLF pep-lab Antifungipept CAFPdb dbAMP i2APP
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
MPKWKVFKKIEKVGRNIRNGIVKAGPAIAVLGEAKALG-NH2
Physicochemical Analysis
C188H320N54O45S1
DCQHSTY
K
4089.00
11.23
9
2
18
+7
8.24
-0.008
105.26
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
134.51
2
Residue Composition
number
5
A
2
R
2
N
0
D
0
C
2
E
0
Q
5
G
0
H
4
I
2
L
7
K
1
M
1
F
2
P
0
S
0
T
1
W
0
Y
4
V
Amino Acid Distribution
A: 5 R: 2 N: 2 D: 0 C: 0 E: 2 Q: 0 G: 5 H: 0 I: 4 L: 2 K: 7 M: 1 F: 1 P: 2 S: 0 T: 0 W: 1 Y: 0 V: 4
Chemical Descriptors
38
C188H320N54O45S1
4089.00
11.23
+7
8.24
-0.008
Amidation
L
Linear
Free
Anticancer
FLAK peptides
Evidence Records 6 records
Evidence 1 Activity

Activity

LD50
LD50 =540 µg/ml
Anticancer
540 µg/mL

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

LD50
LD50 =>1000 µg/ml
Anticancer
>1000 µg/mL

Target

Colon Cancer
SW-480
Colon

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2
Evidence 3 Activity

Activity

LD50
LD50 =>1000 µg/ml
Anticancer
>1000 µg/mL

Target

Skin Cancer
BMKC
Skin

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2
Evidence 4 Activity

Activity

LD50
LD50 =720 µg/ml
Anticancer
720 µg/mL

Target

Lung Cancer
H-1299
Lung

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2
Evidence 5 Activity

Activity

LD50
LD50 =630 µg/ml
Anticancer
630 µg/mL

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2
Evidence 6 Activity

Activity

LD50
LD50 =>1000 µg/ml
Anticancer
>1000 µg/mL

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2