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Peptide record

TPDB91278

Mastoparan Antibacterial Anticancer Antifungal Antiparasitic Antiviral Cell-penetrating Peptides Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB91278
Mastoparan
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia CancerPPD 2.0 SATPdb dbACP Antifungipept CAFPdb DRAVP 2.0 CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acylation
Sequence
INLKALAALAKKIL-NH2
Physicochemical Analysis
C70H130N18O16
RDCEQGHMFPSTWYV
AL
1479.91
10.84
3
0
10
+3
-0.15
1.157
195.71
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
4
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C70H130N18O16
1479.91
10.84
+3
-0.15
1.157
Amidation
L
Amphipathic
Linear
Acylation
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U373MG cells

Assay & Model

Schmidtea mediterranea (planaria)
Schmidtea mediterranea (planaria)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
6-carboxytetramethylrhodamine (TAMRA) dye
Penetrative propensity of 2.5 ± 0.19
In vitro and in vivo
CCSCCHHHHHSCCC
Additional Detail Fields 1 fields
CCSCCHHHHHSCCC