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Peptide record

TPDB91274

PuroA-Lys Antibacterial Anticancer Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91274
PuroA-Lys
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
FPVTWRWWRWWRG-NH2
Physicochemical Analysis
C98H123N27O15
ANDCEQHILKMSY
W
1919.23
12.70
3
0
7
+3
-7.28
-1.054
22.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
27500
1432.87
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
1
F
1
P
0
S
1
T
5
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 0 T: 1 W: 5 Y: 0 V: 1
Chemical Descriptors
13
C98H123N27O15
1919.23
12.70
+3
-7.28
-1.054
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 12.0 µM
Anticancer
12.0 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.