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Peptide record

TPDB91264

SP4 Antibacterial Cell-penetrating Peptides Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB91264
SP4
Antibacterial Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia CPPsite3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GIKFFLKKLKKHI-NH2
Physicochemical Analysis
C80H134N20O14
ARNDCEQMPSTWYV
K
1600.07
11.12
6
0
6
+5
1.92
-0.069
120.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
2
I
2
L
5
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 2 K: 5 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C80H134N20O14
1600.07
11.12
+5
1.92
-0.069
Amidation
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Escherichia Coli Atcc 25,922 Bacterial Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
FITC -conjugated
Cytoplasm
At 3.125 µg/mL and 100 μg/mL, SP4 changes membrane structure and makes it FITC- permeable.
In vitro
CCGGGTSCC
Additional Detail Fields 1 fields
CCGGGTSCC