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Peptide record

TPDB91259

CF-BP16 BP326 Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB91259
CF-BP16 BP326
Antibacterial Anticancer Antifungal Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP CellPPD-MOD CPPsite3.0 PerseuCPP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
KKLFKKILKKL-NH2
Physicochemical Analysis
C69H127N17O12
ARNDCEQGHMPSTWYV
K
1386.87
11.21
6
0
5
+6
2.82
-0.427
141.82
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
6
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 6 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C69H127N17O12
1386.87
11.21
+6
2.82
-0.427
Amidation
L
Cationic
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7, CAPAN-1 and mouse embryonic fibroblast 3T3

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Fluorophore [5(6)-carboxyfluorescein (CF)]
Cytoplasm
High (compare to Tat)
Clathrin mediated endocytosis
In vitro
CTTHHHHTTTC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7, CAPAN-1 and mouse embryonic fibroblast 3T3

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L Cationic
Synthetic
Fluorophore [5(6)-carboxyfluorescein (CF)], CLB
Cytoplasm
High (similar to that of CF-BP16)
In vitro
CTTHHHHTTTC
Additional Detail Fields 1 fields
CTTHHHHTTTC