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Peptide record

TPDB91250

HOOC-(CH2)10-Leu-Enk Antidiabetic Antioxidant Blood-Brain Barrier Neuropeptide standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB91250
HOOC-(CH2)10-Leu-Enk
Antidiabetic Antioxidant Blood-Brain Barrier Neuropeptide
Cardiometabolic peptides Delivery and barrier-penetrating peptides Neuroactive peptides Functional / health-promoting peptides
Peptipedia AnOxPePred - 1.0 AODB AoXpDb Multi-AOP B3Pred BBPpredict
standard
No
A 5-aa standard natural multi-activity (Antidiabetic, Antioxidant, Blood-Brain Barrier, and other sources) peptide sequence curated from Peptipedia, AnOxPePred - 1.0, AODB, and other sources, with an available 3D structural model.
Chemical: Addition of HOOC-(CH2)10 group to Fmoc N-terminal: Addition of HOOC-(CH2)10 group to Fmoc
Sequence
YGGFL
Physicochemical Analysis
C28H37N5O7
ARNDCEQHIKMPSTWV
G
555.63
5.94
0
0
3
-0
-2.61
0.900
78.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
268.16
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
5
C28H37N5O7
555.63
5.94
-0
-2.61
0.900
Addition of HOOC-(CH2)10 group to Fmoc
Linear
Addition of HOOC-(CH2)10 group to Fmoc
Similarity
Tyr-Gly-Gly-Phe-Leu-OH
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier

Assay & Model

Origin/Source
10 micromole/Kg
Hot water tail flick test
Analgesic effect seen within 3 seconds
Alzheimer

Source & Reference

NA
B3Pdb

Other

Intraperitoneal
Additional Detail Fields 1 fields
Intraperitoneal