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Peptide record

TPDB91243

LL37 Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Cell-penetrating Peptides Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB91243
LL37
Antibacterial Anticancer Antifungal Antioxidant Antiparasitic Antiviral Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF Antifungipept CAFPdb dbAMP 3.0 i2APP AI4AVP AVPpred-BWR DRAVP 2.0 CPPsite3.0 APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Physicochemical Analysis
C205H340N60O53
ACHMWY
K
4493.32
11.10
11
5
13
+6
12.83
-0.724
89.46
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
5
Residue Composition
number
0
A
5
R
1
N
2
D
0
C
3
E
1
Q
2
G
0
H
3
I
4
L
6
K
0
M
4
F
1
P
2
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 2 C: 0 E: 3 Q: 1 G: 2 H: 0 I: 3 L: 4 K: 6 M: 0 F: 4 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
37
C205H340N60O53
4493.32
11.10
+6
12.83
-0.724
Free
L
Cationic
Linear
Biotinylation
N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87G Cells And Dermal Human Primary Fibroblasts (Dhf) S. Agalactiae Mutant Nem 316 Δdlta Strain

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Streptavidin–HRP
In vitro
CCHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTCCCC
Additional Detail Fields 1 fields
CCHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTCCCC