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Peptide record

TPDB91242

C1Triazole ACE inhibitors Anticancer Antioxidant standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB91242
C1Triazole
ACE inhibitors Anticancer Antioxidant
Cardiometabolic peptides Cancer-related peptides Functional / health-promoting peptides
Peptipedia CancerPPD 2.0 dbACP AnOxPePred - 1.0 AODB AoXpDb Multi-AOP
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors, Anticancer, and Antioxidant) peptide sequence curated from Peptipedia, CancerPPD 2.0, dbACP, and other sources, with an available 3D structural model.
N-terminal: 4-(4-phenyl-1H-1, 2, 3-triazol-1-yl) benzoic acid
Sequence
GLTSK
Physicochemical Analysis
C21H40N6O8
ARNDCEQHIMFPWYV
GLKST
504.58
10.10
1
0
1
+1
0.71
-0.400
78.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C21H40N6O8
504.58
10.10
+1
0.71
-0.400
Free
L
Linear
4-(4-phenyl-1H-1, 2, 3-triazol-1-yl) benzoic acid
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

59.76 ± 10.34 inhibition % at 10 µM
Anticancer

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2019

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

79.9 ± 0.49 inhibition % at 10 µM
Anticancer

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2019
Evidence 3 Activity

Activity

92.8 ± 0.16 inhibition % at 10 µM
Anticancer

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2019