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Peptide record

TPDB91235

Peptide 6b Anticancer Antioxidant standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB91235
Peptide 6b
Anticancer Antioxidant
Cancer-related peptides Functional / health-promoting peptides
CancerPPD 2.0 AODB Multi-AOP
standard
No
A 2-aa standard natural multi-activity (Anticancer and Antioxidant) peptide sequence curated from CancerPPD 2.0, AODB, and Multi-AOP, with an available 3D structural model.
N-terminal: 4-azidobenzoic acid
Sequence
FD
Physicochemical Analysis
C13H16N2O5
ARNCEQGHILKMPSTWYV
DF
280.28
3.10
0
1
1
-1
0.10
-0.350
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C13H16N2O5
280.28
3.10
-1
0.10
-0.350
Free
L
Linear
4-azidobenzoic acid
Antiproliferative, Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 18.4 ± 0.12 µM
Anticancer
18.4

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 61.5 ± 023µM
Anticancer
61.5

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
Evidence 3 Activity

Activity

IC50
IC50 = 18.6 ± 0.04 µM
Anticancer
18.6

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017