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Peptide record

TPDB91234

DRS B4 Antibacterial Anticancer Antidiabetic Antifungal Antioxidant Antiparasitic standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB91234
DRS B4
Antibacterial Anticancer Antidiabetic Antifungal Antioxidant Antiparasitic
Anti-infective peptides Cardiometabolic peptides Cancer-related peptides Functional / health-promoting peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF Antifungipept
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antidiabetic, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
ALWKDILKNVGKAAGKAVLNTVTDMVNQ-NH2
Physicochemical Analysis
C133H225N37O39S1
RCEHFPSY
AKV
2998.53
10.16
4
2
14
+2
4.09
0.075
111.43
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
183.42
6
Residue Composition
number
4
A
0
R
3
N
2
D
0
C
0
E
1
Q
2
G
0
H
1
I
3
L
4
K
1
M
0
F
0
P
0
S
2
T
1
W
0
Y
4
V
Amino Acid Distribution
A: 4 R: 0 N: 3 D: 2 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 3 K: 4 M: 1 F: 0 P: 0 S: 0 T: 2 W: 1 Y: 0 V: 4
Chemical Descriptors
28
C133H225N37O39S1
2998.53
10.16
+2
4.09
0.075
Amidation
L
Linear
Free
Antimicrobial
Dermaseptins B
Evidence Records 1 records
Evidence 1 Activity

Activity

Cytotoxicity
Cytotoxicity =15 µM
Anticancer

Target

Breast Cancer
MCF-7
Breast

Assay & Model

Thymidine Incorporation assay
6-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1998

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.