Peptide record

TPDB87784

CDP or H–Phe–Phe–NH2. HCl FF-NH2 H-Phe-Phe-NH2 H-Phe-Phe-NH2 .hydrochloride Selfassembly modified_plain modified
2 amino acids
Basic Information
TPDB87784
CDP or H–Phe–Phe–NH2. HCl FF-NH2 H-Phe-Phe-NH2 H-Phe-Phe-NH2 .hydrochloride
Selfassembly
Self-assembling and biomaterial peptides
SAPdb Peptipedia
modified_plain
Yes
A 2-aa modified selfassembly peptide sequence curated from SAPdb and Peptipedia, without an available 3D structural model.
Modified, details unspecified
Sequence
FF-Amidation
Physicochemical Analysis
C53H79N11O15S1
RCEQGHLKPSWYV
AIF
1142.34
3.10
0
1
7
-1
-1.66
1.033
81.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
2
A
0
R
1
N
1
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
1
M
2
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 1 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C53H79N11O15S1
1142.34
3.10
-1
-1.66
1.033
Self-Assembly Information 6 records
Record 1 Selfassembly

Source

28955776
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanotube and vesicle-like structures Nanotubes and vesicle-like structures
pH: 7.4 solvent: Tris-NaCl EDTA (TNE) buffer
Selfassembly; Nanostructure=Nanotube and vesicle-like structures; Nanotubes and vesicle-like structures; Trigger=pH: 7.4; solvent: Tris-NaCl EDTA (TNE) buffer
ultra- violet (UV) absorption spectroscopy, fluorescence spectroscopy, cir- cular dichroism (CD) study, viscosity measurement and thermal dena- turation analysis of DNA
Selfassembly
Record 2 Selfassembly

Source

24036697
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Microsphere
temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Selfassembly; Nanostructure=Microsphere; Trigger=temperature: Room temperature; solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Scanning Electron Microscopy (SEM)
Selfassembly
Record 3 Selfassembly

Source

24036697
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Flower like Nanostructures
temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Selfassembly; Nanostructure=Flower like Nanostructures; Trigger=temperature: Room temperature; solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Scanning Electron Microscopy (SEM)
Selfassembly
Record 4 Selfassembly

Source

24036697
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Plate like Nanostructure
temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Selfassembly; Nanostructure=Plate like Nanostructure; Trigger=temperature: Room temperature; solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Scanning Electron Microscopy (SEM)
Selfassembly
Record 5 Selfassembly

Source

27778498
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanoparticles
pH: 7.4 temperature: 37 °C solvent: phosphate buffer saline (PBS) concentration: 0.5 % (w/v)
Selfassembly; Nanostructure=Nanoparticles; Trigger=pH: 7.4; temperature: 37 °C; solvent: phosphate buffer saline (PBS); concentration: 0.5 % (w/v)
TEM, SEM
Selfassembly
Record 6 Selfassembly

Source

27841381
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanoparticles
pH: 8 temperature: Room temperature solvent: 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)/sodium phosphate buffer concentration: 16 mM
Selfassembly; Nanostructure=Nanoparticles; Trigger=pH: 8; temperature: Room temperature; solvent: 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)/sodium phosphate buffer; concentration: 16 mM
TEM and SEM
Selfassembly
Evidence Records 6 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanotube and vesicle-like structures Nanotubes and vesicle-like structures Trigger=pH: 7.4 solvent: Tris-NaCl EDTA (TNE) buffer
Nanotube and vesicle-like structures Nanotubes and vesicle-like structures

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

C-terminal: Amidation
pH: 7.4 solvent: Tris-NaCl EDTA (TNE) buffer
ultra- violet (UV) absorption spectroscopy, fluorescence spectroscopy, cir- cular dichroism (CD) study, viscosity measurement and thermal dena- turation analysis of DNA
28955776
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 2 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Microsphere Trigger=temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Microsphere

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

C-terminal: Amidation
temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Scanning Electron Microscopy (SEM)
24036697
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1355 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Evidence 3 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Flower like Nanostructures Trigger=temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Flower like Nanostructures

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

C-terminal: Amidation
temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Scanning Electron Microscopy (SEM)
24036697
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1356 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Evidence 4 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Plate like Nanostructure Trigger=temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Plate like Nanostructure

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

C-terminal: Amidation
temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
Scanning Electron Microscopy (SEM)
24036697
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1357 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Evidence 5 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanoparticles Trigger=pH: 7.4 temperature: 37 °C solvent: phosphate buffer saline (PBS) concentration: 0.5 % (w/v)
Nanoparticles

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

C-terminal: Amidation
pH: 7.4 temperature: 37 °C solvent: phosphate buffer saline (PBS) concentration: 0.5 % (w/v)
TEM, SEM
27778498
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1884 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Evidence 6 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanoparticles Trigger=pH: 8 temperature: Room temperature solvent: 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)/sodium phosphate buffer concentration: 16 mM
Nanoparticles

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

C-terminal: Amidation
pH: 8 temperature: Room temperature solvent: 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)/sodium phosphate buffer concentration: 16 mM
TEM and SEM
27841381
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1887 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Additional Detail Fields 5 fields
pH: 7.4 solvent: Tris-NaCl EDTA (TNE) buffer temperature: Room temperature solvent: HFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water temperature: 37 °C solvent: phosphate buffer saline (PBS) concentration: 0.5 % (w/v) pH: 8 solvent: 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)/sodium phosphate buffer concentration: 16 mM
C-terminal: Amidation
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database. SAPdb ID 1355 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row. SAPdb ID 1356 SAPdb ID 1357 SAPdb ID 1884 SAPdb ID 1887
28955776 24036697 27778498 27841381
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly