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Peptide record

TPDB87721

Fmoc-NPhe-NPhe (Compound 4) Selfassembly modified_plain modified
2 amino acids
Basic Information
TPDB87721
Fmoc-NPhe-NPhe (Compound 4)
Selfassembly
Self-assembling and biomaterial peptides
SAPdb
modified_plain
Yes
A 2-aa modified selfassembly peptide sequence curated from SAPdb, without an available 3D structural model.
Modified, details unspecified
Sequence
Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]-Nphe-Nphe-Nphe
Physicochemical Analysis
C192H276N58O56S4
DQGIKSWV
N
4420.90
6.03
7
5
11
-2
12.51
-0.832
22.68
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
4595
103.94
12
Residue Composition
number
1
A
3
R
6
N
0
D
2
C
5
E
0
Q
0
G
4
H
0
I
3
L
0
K
2
M
2
F
3
P
0
S
1
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 6 D: 0 C: 2 E: 5 Q: 0 G: 0 H: 4 I: 0 L: 3 K: 0 M: 2 F: 2 P: 3 S: 0 T: 1 W: 0 Y: 3 V: 0
Chemical Descriptors
2
C192H276N58O56S4
4420.90
6.03
-2
12.51
-0.832
Self-Assembly Information 1 records
Record 1 Selfassembly

Source

27696352
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanofiber Fibrils
pH: 7.1–7.6 temperature: 60 °C solvent: glucono-d-lactone (GdL) concentration: 18 mM
Selfassembly; Nanostructure=Nanofiber; Fibrils; Trigger=pH: 7.1–7.6; temperature: 60 °C; solvent: glucono-d-lactone (GdL); concentration: 18 mM
Circular dichroism spectroscopy, FT-IR spectroscopy, NMR spectroscopy, TEM, HPLC, PAD-X and Rheology
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanofiber Fibrils Trigger=pH: 7.1–7.6 temperature: 60 °C solvent: glucono-d-lactone (GdL) concentration: 18 mM
Nanofiber Fibrils

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)] C-terminal: Nphe
pH: 7.1–7.6 temperature: 60 °C solvent: glucono-d-lactone (GdL) concentration: 18 mM
Circular dichroism spectroscopy, FT-IR spectroscopy, NMR spectroscopy, TEM, HPLC, PAD-X and Rheology
27696352
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Additional Detail Fields 5 fields
pH: 7.1–7.6 temperature: 60 °C solvent: glucono-d-lactone (GdL) concentration: 18 mM
N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)] C-terminal: Nphe
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
27696352
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly