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Peptide record

TPDB87586

Dipeptide 3 Fmoc-tyrosine-leucine (FmocYL) Fmoc-YL YL Selfassembly modified_plain modified
2 amino acids
Basic Information
TPDB87586
Dipeptide 3 Fmoc-tyrosine-leucine (FmocYL) Fmoc-YL YL
Selfassembly
Self-assembling and biomaterial peptides
SAPdb Peptipedia
modified_plain
Yes
A 2-aa modified selfassembly peptide sequence curated from SAPdb and Peptipedia, without an available 3D structural model.
Modified, details unspecified
Sequence
Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]-YL
Physicochemical Analysis
C147H215N39O38S4
DQGIKPSWV
LY
3264.80
8.25
4
2
13
+1
-0.54
-0.198
37.73
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6085
186.38
10
Residue Composition
number
1
A
3
R
3
N
0
D
2
C
2
E
0
Q
0
G
1
H
0
I
4
L
0
K
2
M
2
F
0
P
0
S
1
T
0
W
4
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 3 D: 0 C: 2 E: 2 Q: 0 G: 0 H: 1 I: 0 L: 4 K: 0 M: 2 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 4 V: 0
Chemical Descriptors
2
C147H215N39O38S4
3264.80
8.25
+1
-0.54
-0.198
Self-Assembly Information 4 records
Record 1 Selfassembly

Source

24256076
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Hydogel (consists of Nanofibers)
pH: 8 temperature: Room temperature solvent: 100mM Phosphate buffer concentration: 10mM
Selfassembly; Nanostructure=Hydrogel; Hydogel (consists of Nanofibers); Trigger=pH: 8; temperature: Room temperature; solvent: 100mM Phosphate buffer; concentration: 10mM
AFM (Atomic Force Microscopy, Fluorescence Emission Spectroscopy and DLS (Dynamic Light Scattering)
Selfassembly
Record 2 Selfassembly

Source

21107375
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Transparent gel
pH: 8 temperature: Intial 55 °C heating for 1 hour and followed by cooling at room temperature solvent: Sodium phosphate buffer (pH 8) concentration: 10 mmol/kg
Selfassembly; Nanostructure=Hydrogel; Transparent gel; Trigger=pH: 8; temperature: Intial 55 °C heating for 1 hour and followed by cooling at room temperature; solvent: Sodium phosphate buffer (pH 8); concentration: 10 mmol/kg
AFM (Atomic Force Microscopy) and DLS (Dynamic Light Scattering)
Selfassembly
Record 3 Selfassembly

Source

24896538
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Gel (consist of Fibrous network)
pH: 8 temperature: Room temperature solvent: Phosphate buffer concentration: 10mM
Selfassembly; Nanostructure=Hydrogel; Gel (consist of Fibrous network); Trigger=pH: 8; temperature: Room temperature; solvent: Phosphate buffer; concentration: 10mM
Scanning Electron Microscopy (SEM) and AFM (Atomic force Microscopy)
Selfassembly
Record 4 Selfassembly

Source

28703237
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanofiber Nanofibres
Selfassembly; Nanostructure=Nanofiber; Nanofibres
FTIR
Selfassembly
Evidence Records 4 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Hydogel (consists of Nanofibers) Trigger=pH: 8 temperature: Room temperature solvent: 100mM Phosphate buffer concentration: 10mM
Hydrogel Hydogel (consists of Nanofibers)

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 8 temperature: Room temperature solvent: 100mM Phosphate buffer concentration: 10mM
AFM (Atomic Force Microscopy, Fluorescence Emission Spectroscopy and DLS (Dynamic Light Scattering)
24256076
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 2 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Transparent gel Trigger=pH: 8 temperature: Intial 55 °C heating for 1 hour and followed by cooling at room temperature solvent: Sodium phosphate buffer (pH 8) concentration: 10 mmol/kg
Hydrogel Transparent gel

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 8 temperature: Intial 55 °C heating for 1 hour and followed by cooling at room temperature solvent: Sodium phosphate buffer (pH 8) concentration: 10 mmol/kg
AFM (Atomic Force Microscopy) and DLS (Dynamic Light Scattering)
21107375
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 3 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Gel (consist of Fibrous network) Trigger=pH: 8 temperature: Room temperature solvent: Phosphate buffer concentration: 10mM
Hydrogel Gel (consist of Fibrous network)

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 8 temperature: Room temperature solvent: Phosphate buffer concentration: 10mM
Scanning Electron Microscopy (SEM) and AFM (Atomic force Microscopy)
24896538
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 4 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanofiber Nanofibres
Nanofiber Nanofibres

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
FTIR
28703237
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Additional Detail Fields 5 fields
pH: 8 temperature: Room temperature solvent: 100mM Phosphate buffer concentration: 10mM temperature: Intial 55 °C heating for 1 hour and followed by cooling at room temperature solvent: Sodium phosphate buffer (pH 8) concentration: 10 mmol/kg solvent: Phosphate buffer
N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
24256076 21107375 24896538 28703237
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly