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Peptide record

TPDB87573

(Fmoc-AA) Fmoc-AA Fmoc-AA-OH Fmoc-di-alanine (Fmoc-AA) N-(fluorenyl-9-methoxycarbonyl)-D-Ala-D-Ala Selfassembly modified_plain modified
2 amino acids
Basic Information
TPDB87573
(Fmoc-AA) Fmoc-AA Fmoc-AA-OH Fmoc-di-alanine (Fmoc-AA) N-(fluorenyl-9-methoxycarbonyl)-D-Ala-D-Ala
Selfassembly
Self-assembling and biomaterial peptides
SAPdb Peptipedia
modified_plain
Yes
A 2-aa modified selfassembly peptide sequence curated from SAPdb and Peptipedia, without an available 3D structural model.
Modified, details unspecified
Sequence
Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]-AA
Physicochemical Analysis
C138H205N39O37S4
DQGIKPSWV
ARNLY
3130.62
8.26
4
2
13
+1
0.62
-0.173
33.41
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
4595
146.78
9
Residue Composition
number
3
A
3
R
3
N
0
D
2
C
2
E
0
Q
0
G
1
H
0
I
3
L
0
K
2
M
2
F
0
P
0
S
1
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 3 R: 3 N: 3 D: 0 C: 2 E: 2 Q: 0 G: 0 H: 1 I: 0 L: 3 K: 0 M: 2 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 3 V: 0
Chemical Descriptors
2
C138H205N39O37S4
3130.62
8.26
+1
0.62
-0.173
Self-Assembly Information 7 records
Record 1 Selfassembly

Source

23020140
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Hydrogel (Nanoribbon)
pH: 3.3 - 3.4 temperature: Room temperature solvent: Water + 0.1M Hcl + 0.5 M NaOH concentration: 5mg/ml
Selfassembly; Nanostructure=Hydrogel; Hydrogel (Nanoribbon); Trigger=pH: 3.3 - 3.4; temperature: Room temperature; solvent: Water + 0.1M Hcl + 0.5 M NaOH; concentration: 5mg/ml
Transmission Electron Microscopy (TEM), AFM (Atomic Force Microscopy), UV - vis - NIR, FTIR (Fourier - transform infrared spectroscopy) and CD (Circular Dichroism spectroscopy)
Selfassembly
Record 2 Selfassembly

Source

24786493
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Hydrogel (flat, ribbon like structures)
pH: 3.1 - 3.5 solvent: 1 equiv of 0.5 M NaOH + 1 equiv of 0.1 M HCl concentration: 5mg/ml
Selfassembly; Nanostructure=Hydrogel; Hydrogel (flat, ribbon like structures); Trigger=pH: 3.1 - 3.5; solvent: 1 equiv of 0.5 M NaOH + 1 equiv of 0.1 M HCl; concentration: 5mg/ml
Transmission Electron Microscopy (TEM)
Selfassembly
Record 3 Selfassembly

Source

30034729
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanofiber nanofibers
pH: 8.5 temperature: Room temperature solvent: Poly(diallyldimethylammonium chloride) (PDDA) concentration: Milli‐Q water
Selfassembly; Nanostructure=Nanofiber; nanofibers; Trigger=pH: 8.5; temperature: Room temperature; solvent: Poly(diallyldimethylammonium chloride) (PDDA); concentration: Milli‐Q water
Transmission Electron Microscopy (TEM)
Selfassembly
Record 4 Selfassembly

Source

30307451
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanostructure nanostructures
pH: 7 temperature: Room temperature solvent: bulk water solution
Selfassembly; Nanostructure=Nanostructure; nanostructures; Trigger=pH: 7; temperature: Room temperature; solvent: bulk water solution
UV-vis spectroscopy and BAM
Selfassembly
Record 5 Selfassembly

Source

30950622
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanostructure nanomaterials
pH: 2 temperature: 21 °C solvent: methanol concentration: 1mM
Selfassembly; Nanostructure=Nanostructure; nanomaterials; Trigger=pH: 2; temperature: 21 °C; solvent: methanol; concentration: 1mM
UV−Vis Reflection Spectroscopy and Brewster Angle Microscopy
Selfassembly
Record 6 Selfassembly

Source

27722469
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanostructure Nanostructures
temperature: 0 to 298K
Selfassembly; Nanostructure=Nanostructure; Nanostructures; Trigger=temperature: 0 to 298K
FTIR, CD, fluorescence
Selfassembly
Record 7 Selfassembly

Source

29063660
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanostructure Nanostructures
pH: 7 solvent: Fmoc- AA-OH/glucose solution concentration: 500 μL/min
Selfassembly; Nanostructure=Nanostructure; Nanostructures; Trigger=pH: 7; solvent: Fmoc- AA-OH/glucose solution; concentration: 500 μL/min
Attenuated total reflectance Fourier transformed infrared spectroscopy (ATR-FTIR), (AFM), (SEM) and cryo-SEM
Selfassembly
Evidence Records 7 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Hydrogel (Nanoribbon) Trigger=pH: 3.3 - 3.4 temperature: Room temperature solvent: Water + 0.1M Hcl + 0.5 M NaOH concentration: 5mg/ml
Hydrogel Hydrogel (Nanoribbon)

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 3.3 - 3.4 temperature: Room temperature solvent: Water + 0.1M Hcl + 0.5 M NaOH concentration: 5mg/ml
Transmission Electron Microscopy (TEM), AFM (Atomic Force Microscopy), UV - vis - NIR, FTIR (Fourier - transform infrared spectroscopy) and CD (Circular Dichroism spectroscopy)
23020140
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 2 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Hydrogel (flat, ribbon like structures) Trigger=pH: 3.1 - 3.5 solvent: 1 equiv of 0.5 M NaOH + 1 equiv of 0.1 M HCl concentration: 5mg/ml
Hydrogel Hydrogel (flat, ribbon like structures)

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 3.1 - 3.5 solvent: 1 equiv of 0.5 M NaOH + 1 equiv of 0.1 M HCl concentration: 5mg/ml
Transmission Electron Microscopy (TEM)
24786493
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 3 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanofiber nanofibers Trigger=pH: 8.5 temperature: Room temperature solvent: Poly(diallyldimethylammonium chloride) (PDDA) concentration: Milli‐Q water
Nanofiber nanofibers

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 8.5 temperature: Room temperature solvent: Poly(diallyldimethylammonium chloride) (PDDA) concentration: Milli‐Q water
Transmission Electron Microscopy (TEM)
30034729
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 4 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanostructure nanostructures Trigger=pH: 7 temperature: Room temperature solvent: bulk water solution
Nanostructure nanostructures

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 7 temperature: Room temperature solvent: bulk water solution
UV-vis spectroscopy and BAM
30307451
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 5 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanostructure nanomaterials Trigger=pH: 2 temperature: 21 °C solvent: methanol concentration: 1mM
Nanostructure nanomaterials

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 2 temperature: 21 °C solvent: methanol concentration: 1mM
UV−Vis Reflection Spectroscopy and Brewster Angle Microscopy
30950622
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 6 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanostructure Nanostructures Trigger=temperature: 0 to 298K
Nanostructure Nanostructures

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
temperature: 0 to 298K
FTIR, CD, fluorescence
27722469
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 7 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanostructure Nanostructures Trigger=pH: 7 solvent: Fmoc- AA-OH/glucose solution concentration: 500 μL/min
Nanostructure Nanostructures

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
pH: 7 solvent: Fmoc- AA-OH/glucose solution concentration: 500 μL/min
Attenuated total reflectance Fourier transformed infrared spectroscopy (ATR-FTIR), (AFM), (SEM) and cryo-SEM
29063660
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Additional Detail Fields 5 fields
pH: 3.3 - 3.4 temperature: Room temperature solvent: Water + 0.1M Hcl + 0.5 M NaOH concentration: 5mg/ml pH: 3.1 - 3.5 solvent: 1 equiv of 0.5 M NaOH + 1 equiv of 0.1 M HCl pH: 8.5 solvent: Poly(diallyldimethylammonium chloride) (PDDA) concentration: Milli‐Q water pH: 7 solvent: bulk water solution pH: 2 temperature: 21 °C solvent: methanol concentration: 1mM temperature: 0 to 298K solvent: Fmoc- AA-OH/glucose solution concentration: 500 μL/min
N-terminal: Fmoc [or N-(fluorenyl-9-methoxycarbonyl)]
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
23020140 24786493 30034729 30307451 30950622 27722469 29063660
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly