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Peptide record

TPDB87571

beta-dehydroPhenylalanine Leu-alpha Leucine-dehydroPhenylalanine (L-Delta-F) LeuΔPhe (Leucine-α, β-dehydroPhenylalanine) Selfassembly modified_plain modified
3 amino acids
Basic Information
TPDB87571
beta-dehydroPhenylalanine Leu-alpha Leucine-dehydroPhenylalanine (L-Delta-F) LeuΔPhe (Leucine-α, β-dehydroPhenylalanine)
Selfassembly
Self-assembling and biomaterial peptides
SAPdb
modified_plain
Yes
A 3-aa modified selfassembly peptide sequence curated from SAPdb, without an available 3D structural model.
Modified, details unspecified
Sequence
L-Delta-F-Delta-F or Δphe=alpha-beta-dehydrophenylalanine
Physicochemical Analysis
C225H331N61O75
CQGKMSWV
AE
5090.47
4.18
6
11
18
-9
18.55
-0.600
59.14
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
58.54
8
Residue Composition
number
7
A
2
R
3
N
4
D
0
C
7
E
0
Q
0
G
4
H
1
I
6
L
0
K
0
M
2
F
3
P
0
S
3
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 7 R: 2 N: 3 D: 4 C: 0 E: 7 Q: 0 G: 0 H: 4 I: 1 L: 6 K: 0 M: 0 F: 2 P: 3 S: 0 T: 3 W: 0 Y: 2 V: 0
Chemical Descriptors
3
C225H331N61O75
5090.47
4.18
-9
18.55
-0.600
Self-Assembly Information 3 records
Record 1 Selfassembly

Source

22915849
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanofiber Fibrillar structures
temperature: Room temperature solvent: Methanol and water (50:50 v/v). concentration: 2mg/ml
Selfassembly; Nanostructure=Nanofiber; Fibrillar structures; Trigger=temperature: Room temperature; solvent: Methanol and water (50:50; v/v).; concentration: 2mg/ml
Transmission Electron Microscopy (TEM), DLS (Dynamic light - scattering)
Selfassembly
Record 2 Selfassembly

Source

27507432
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Hydrogels
pH: 7 temperature: 37 °C solvent: sodium acetate buffer concentration: 0.8 M
Selfassembly; Nanostructure=Hydrogel; Hydrogels; Trigger=pH: 7; temperature: 37 °C; solvent: sodium acetate buffer; concentration: 0.8 M
TEM, SEM, ESEM,CD and FTIR spectroscopy.
Selfassembly
Record 3 Selfassembly

Source

22833945
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Small micellar structure
temperature: Room temperature solvent: 1,1,1,3,3,3-hexa-fluoro-isopropanol/water. concentration: 0.1 - 1mg/ml
Selfassembly; Nanostructure=Small micellar structure; Trigger=temperature: Room temperature; solvent: 1,1,1,3,3,3-hexa-fluoro-isopropanol/water.; concentration: 0.1 - 1mg/ml
Transmission Electron Microscopy (TEM) and DLS (Dynamic Light scattering)
Selfassembly
Evidence Records 3 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanofiber Fibrillar structures Trigger=temperature: Room temperature solvent: Methanol and water (50:50 v/v). concentration: 2mg/ml
Nanofiber Fibrillar structures

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

Other: Delta-F or Δphe=alpha-beta-dehydrophenylalanine
temperature: Room temperature solvent: Methanol and water (50:50 v/v). concentration: 2mg/ml
Transmission Electron Microscopy (TEM), DLS (Dynamic light - scattering)
22915849
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 2 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Hydrogels Trigger=pH: 7 temperature: 37 °C solvent: sodium acetate buffer concentration: 0.8 M
Hydrogel Hydrogels

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

Other: Delta-F or Δphe=alpha-beta-dehydrophenylalanine
pH: 7 temperature: 37 °C solvent: sodium acetate buffer concentration: 0.8 M
TEM, SEM, ESEM,CD and FTIR spectroscopy.
27507432
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 3 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Small micellar structure Trigger=temperature: Room temperature solvent: 1,1,1,3,3,3-hexa-fluoro-isopropanol/water. concentration: 0.1 - 1mg/ml
Small micellar structure

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

Other: Delta-F or Δphe=alpha-beta-dehydrophenylalanine
temperature: Room temperature solvent: 1,1,1,3,3,3-hexa-fluoro-isopropanol/water. concentration: 0.1 - 1mg/ml
Transmission Electron Microscopy (TEM) and DLS (Dynamic Light scattering)
22833945
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1492 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Additional Detail Fields 5 fields
temperature: Room temperature solvent: Methanol and water (50:50 v/v). concentration: 2mg/ml pH: 7 temperature: 37 °C solvent: sodium acetate buffer concentration: 0.8 M solvent: 1,1,1,3,3,3-hexa-fluoro-isopropanol/water. concentration: 0.1 - 1mg/ml
Other: Delta-F or Δphe=alpha-beta-dehydrophenylalanine
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database. SAPdb ID 1492 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
22915849 27507432 22833945
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly