TPDB

TPDB ID TPDB87570

Peptide_Name

Methionine-dehydroPhenylalanine (M-Delta-F)

Activity

Selfassembly

Activity_category_statistics

Self-assembling and biomaterial peptides

Database_Source

SAPdb

Sequence_Type

modified_plain

Has_Modification Yes

Description A 3-aa modified selfassembly peptide sequence curated from SAPdb, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

M-Delta-F-Delta-F or Î”phe=alpha-beta-dehydrophenylalanine

FASTA

>TPDB87570|Selfassembly|length=3
M-Delta-F-Delta-F or Î”phe=alpha-beta-dehydrophenylalanine

Formula C224H329N61O75S1

Absent Amino Acids CQGKSWV

Common Amino Acids AE

Mass 5108.50

PI 4.18

Basic Residues 6

Acidic Residues 11

Hydrophobic Residues 18

Net Charge -9

Boman Index 18.88

Hydrophobicity -0.633

Aliphatic Index 52.41

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 2980

Absorbance 280nm 58.33

Polar Residues 8

number

7

A

2

R

3

N

4

D

0

C

7

E

0

Q

0

G

4

H

1

I

5

L

0

K

1

M

2

F

3

P

0

S

3

T

0

W

2

Y

0

V

Amino Acid Distribution

A: 7 R: 2 N: 3 D: 4 C: 0 E: 7 Q: 0 G: 0 H: 4 I: 1 L: 5 K: 0 M: 1 F: 2 P: 3 S: 0 T: 3 W: 0 Y: 2 V: 0

Length

3

Formula

C224H329N61O75S1

Mass

5108.50

PI

4.18

Net Charge

-9

Boman Index

18.88

Hydrophobicity

-0.633

Record 1 Selfassembly

Source

PMID 22915849

DOI 10.1016/j.compbiomed.2021.104391

Title

SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Activity Endpoint Nanostructure formation

Nanostructure Nanoparticle, Nanovesicle Monodispersed Nanoparticles or vesicular structures

Assembly Trigger temperature: Room temperature solvent: Methanol and water (50:50 v/v). concentration: 2mg/ml

Source Annotation

Selfassembly; Nanostructure=Nanoparticle, Nanovesicle; Monodispersed Nanoparticles or vesicular structures; Trigger=temperature: Room temperature; solvent: Methanol and water (50:50; v/v).; concentration: 2mg/ml

Assembly Evidence Transmission Electron Microscopy (TEM), DLS (Dynamic light - scattering)

Source Activity Label Selfassembly

Evidence 1 Selfassembly

Activity

Activity Endpoint Nanostructure formation

Activity Raw

Selfassembly Nanostructure=Nanoparticle, Nanovesicle Monodispersed Nanoparticles or vesicular structures Trigger=temperature: Room temperature solvent: Methanol and water (50:50 v/v). concentration: 2mg/ml

Detail Activity Nanoparticle, Nanovesicle Monodispersed Nanoparticles or vesicular structures

Source & Reference

Database Source SAPdb

DOI 10.1016/j.compbiomed.2021.104391

Other

Modification Other: Delta-F or Î”phe=alpha-beta-dehydrophenylalanine

Assembly Trigger temperature: Room temperature solvent: Methanol and water (50:50 v/v). concentration: 2mg/ml

Evidence Text

Transmission Electron Microscopy (TEM), DLS (Dynamic light - scattering)

PMID 22915849

Reference Title SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Notes SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.

Assembly_Trigger

temperature: Room temperature solvent: Methanol and water (50:50 v/v). concentration: 2mg/ml

Modification

Other: Delta-F or Î”phe=alpha-beta-dehydrophenylalanine

Notes

SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.

PMID

22915849

Reference_Title

SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly