TPDB

TPDB ID TPDB87496

Peptide_Name

Boc-Trp-Ile-Ile-OMe

Activity

Selfassembly

Activity_category_statistics

Self-assembling and biomaterial peptides

Database_Source

SAPdb

Sequence_Type

modified_plain

Has_Modification Yes

Description A 3-aa modified selfassembly peptide sequence curated from SAPdb, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

Boc (or t-butoxycarbonyl)-WII-Methoxy

FASTA

>TPDB87496|Selfassembly|length=3
Boc (or t-butoxycarbonyl)-WII-Methoxy

Formula C109H161N29O29S3

Absent Amino Acids DQGKFPSV

Common Amino Acids TY

Mass 2437.83

PI 8.26

Basic Residues 3

Acidic Residues 1

Hydrophobic Residues 9

Net Charge +1

Boman Index -1.29

Hydrophobicity -0.124

Aliphatic Index 34.32

Half Life

Mammalian: Yeast: E.coli:

Extinction Coefficient Cystines 10095

Absorbance 280nm 414.10

Polar Residues 9

number

1

A

2

R

1

N

0

D

2

C

1

E

0

Q

0

G

1

H

2

I

1

L

0

K

1

M

0

F

0

P

0

S

3

T

1

W

3

Y

0

V

Amino Acid Distribution

A: 1 R: 2 N: 1 D: 0 C: 2 E: 1 Q: 0 G: 0 H: 1 I: 2 L: 1 K: 0 M: 1 F: 0 P: 0 S: 0 T: 3 W: 1 Y: 3 V: 0

Length

3

Formula

C109H161N29O29S3

Mass

2437.83

PI

8.26

Net Charge

+1

Boman Index

-1.29

Hydrophobicity

-0.124

Record 1 Selfassembly

Source

PMID 22431418

DOI 10.1016/j.compbiomed.2021.104391

Title

SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Activity Endpoint Nanostructure formation

Nanostructure Nanotube, Nanosphere Branched tubular structure and globular Structure

Assembly Trigger temperature: Room temperature solvent: Methanol concentration: 2-5mg/ml

Source Annotation

Selfassembly; Nanostructure=Nanotube, Nanosphere; Branched tubular structure and globular Structure; Trigger=temperature: Room temperature; solvent: Methanol; concentration: 2-5mg/ml

Assembly Evidence

Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), DLS (Dynamic Light Scattering), CD (Circular Dichroism spectroscopy), and FTIR (Fourier Transform Infrared) Spectroscopy (Fourier Transform Infrared) Spectroscopy

Source Activity Label Selfassembly

Evidence 1 Selfassembly

Activity

Activity Endpoint Nanostructure formation

Activity Raw

Selfassembly Nanostructure=Nanotube, Nanosphere Branched tubular structure and globular Structure Trigger=temperature: Room temperature solvent: Methanol concentration: 2-5mg/ml

Detail Activity Nanotube, Nanosphere Branched tubular structure and globular Structure

Source & Reference

Database Source SAPdb

DOI 10.1016/j.compbiomed.2021.104391

Other

Modification N-terminal: Boc (or t-butoxycarbonyl) C-terminal: Methoxy

Assembly Trigger temperature: Room temperature solvent: Methanol concentration: 2-5mg/ml

Evidence Text

Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), DLS (Dynamic Light Scattering), CD (Circular Dichroism spectroscopy), and FTIR (Fourier Transform Infrared) Spectroscopy (Fourier Transform Infrared) Spectroscopy

PMID 22431418

Reference Title SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Notes SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.

Assembly_Trigger

temperature: Room temperature solvent: Methanol concentration: 2-5mg/ml

Modification

N-terminal: Boc (or t-butoxycarbonyl) C-terminal: Methoxy

Notes

SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.

PMID

22431418

Reference_Title

SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly