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Peptide record

TPDB87461

Boc-diPhenylalanine Boc-FLFL Boc-Phe-Phe-COOH Boc-Phe-Phe-OH Boc-Phe-Phe-OH and NH2-Phe-Phe-OH Boc-β(O)-δ5-Phe-β(O)-δ5-Phe NH2-Phe-Phe-OH + Boc-Phe-Phe-COOH Phe-Phe motif Selfassembly modified_plain modified
2 amino acids
Basic Information
TPDB87461
Boc-diPhenylalanine Boc-FLFL Boc-Phe-Phe-COOH Boc-Phe-Phe-OH Boc-Phe-Phe-OH and NH2-Phe-Phe-OH Boc-β(O)-δ5-Phe-β(O)-δ5-Phe NH2-Phe-Phe-OH + Boc-Phe-Phe-COOH Phe-Phe motif
Selfassembly
Self-assembling and biomaterial peptides
SAPdb Peptipedia
modified_plain
Yes
A 2-aa modified selfassembly peptide sequence curated from SAPdb and Peptipedia, without an available 3D structural model.
Modified, details unspecified
Sequence
Boc (or t-butoxycarbonyl)-FF
Physicochemical Analysis
C75H108N20O19S2
DEQGHIKMPSWV
RCFTY
1657.93
9.02
2
0
6
+2
-3.03
-0.011
17.50
Mammalian: Yeast: E.coli:
3105
187.28
7
Residue Composition
number
1
A
2
R
1
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
2
F
0
P
0
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
2
C75H108N20O19S2
1657.93
9.02
+2
-3.03
-0.011
Self-Assembly Information 13 records
Record 1 Selfassembly

Source

18035858
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanosphere
solvent: Aqueous dispersion concentration: 5 mg/ml
Selfassembly; Nanostructure=Nanosphere; Trigger=solvent: Aqueous dispersion; concentration: 5 mg/ml
Scanning Electron Microscopy (SEM)
Selfassembly
Record 2 Selfassembly

Source

18035858
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanotube
solvent: Aqueous dispersion concentration: 2 mg/ml
Selfassembly; Nanostructure=Nanotube; Trigger=solvent: Aqueous dispersion; concentration: 2 mg/ml
Scanning Electron Microscopy (SEM)
Selfassembly
Record 3 Selfassembly

Source

23061818
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanosphere spherical structures
pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 1mg/ml (1st dipeptide) + 1mg/ml )2nd dipeptide
Selfassembly; Nanostructure=Nanosphere; spherical structures; Trigger=pH: ~ 4.5; temperature: Room temperature; solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl; concentration: 1mg/ml (1st dipeptide) + 1mg/ml )2nd dipeptide
Scanning Electron Microscopy (SEM), HR - SEM (High Resolution Scanning Electron Microscopy), Transmission Electron Microscopy (TEM), AFM (Atomic force Microscopy)
Selfassembly
Record 4 Selfassembly

Source

25391268
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanosphere Spherical structures
temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
Selfassembly; Nanostructure=Nanosphere; Spherical structures; Trigger=temperature: Room temperature; solvent: 10% ethanol in water; concentration: 0.2 - 10mg/ml
HR - SEM (High Resolution Scanning Electron Microscopy) and DLS (Dynamic light scattering)
Selfassembly
Record 5 Selfassembly

Source

25391268
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanofiber Fibril Nanostructure
temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
Selfassembly; Nanostructure=Nanofiber; Fibril Nanostructure; Trigger=temperature: Room temperature; solvent: 10% ethanol in water; concentration: 0.2 - 10mg/ml
HR - SEM (High Resolution Scanning Electron Microscopy) and DLS (Dynamic light scattering)
Selfassembly
Record 6 Selfassembly

Source

25391268
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanotube
temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
Selfassembly; Nanostructure=Nanotube; Trigger=temperature: Room temperature; solvent: 10% ethanol in water; concentration: 0.2 - 10mg/ml
HR - SEM (High Resolution Scanning Electron Microscopy) and DLS (Dynamic light scattering)
Selfassembly
Record 7 Selfassembly

Source

24301009
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanosphere
temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + Ethanol concentration: 5mg/ml
Selfassembly; Nanostructure=Nanosphere; Trigger=temperature: Room temperature; solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + Ethanol; concentration: 5mg/ml
Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and AFM (Atomic Force Microscopy)
Selfassembly
Record 8 Selfassembly

Source

29379926
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanostructure nanovasicles
temperature: Room temperature solvent: 1,1,1,3,3,3-hexafluoro-2- propanol (HFIP), lyopHilized concentration: 3mg/ml
Selfassembly; Nanostructure=Nanostructure; nanovasicles; Trigger=temperature: Room temperature; solvent: 1,1,1,3,3,3-hexafluoro-2- propanol (HFIP), lyopHilized; concentration: 3mg/ml
SEM, HRTEM, AFM
Selfassembly
Record 9 Selfassembly

Source

30753058
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel
temperature: 60−80 °C solvent: Ethyl acetate and petroleum ether
Selfassembly; Nanostructure=Hydrogel; Trigger=temperature: 60−80 °C; solvent: Ethyl acetate and petroleum ether
Selfassembly
Record 10 Selfassembly

Source

27582363
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Nanosphere Spheres, fibrils and tubes
solvent: Water
Selfassembly; Nanostructure=Nanosphere; Spheres, fibrils and tubes; Trigger=solvent: Water
Scanning Electron Microscopy (SEM)
Selfassembly
Record 11 Selfassembly

Source

23061818
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Spherical structures with branching fibers
pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 5mg/ml (1st dipeptide) + 2mg/ml )2nd dipeptide
Selfassembly; Nanostructure=Spherical structures with branching fibers; Trigger=pH: ~ 4.5; temperature: Room temperature; solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl; concentration: 5mg/ml (1st dipeptide) + 2mg/ml )2nd dipeptide
Scanning Electron Microscopy (SEM), HR - SEM (High Resolution Scanning Electron Microscopy), Transmission Electron Microscopy (TEM), AFM (Atomic force Microscopy)
Selfassembly
Record 12 Selfassembly

Source

23061818
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Necklaces like Nanostructue
pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 3mg/ml (1st dipeptide) + 3mg/ml )2nd dipeptide
Selfassembly; Nanostructure=Necklaces like Nanostructue; Trigger=pH: ~ 4.5; temperature: Room temperature; solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl; concentration: 3mg/ml (1st dipeptide) + 3mg/ml )2nd dipeptide
Scanning Electron Microscopy (SEM), HR - SEM (High Resolution Scanning Electron Microscopy), Transmission Electron Microscopy (TEM), AFM (Atomic force Microscopy)
Selfassembly
Record 13 Selfassembly

Source

24301009
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Necklaces like Nanostructue
temperature: Room temperature solvent: HFP+50 % Ethanol concentration: 5mg/ml (1st dipeptide) and 3mg/ml (2nd dipeptide)
Selfassembly; Nanostructure=Necklaces like Nanostructue; Trigger=temperature: Room temperature; solvent: HFP+50 % Ethanol; concentration: 5mg/ml (1st dipeptide) and 3mg/ml (2nd dipeptide)
Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and AFM (Atomic Force Microscopy)
Selfassembly
Evidence Records 13 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanosphere Trigger=solvent: Aqueous dispersion concentration: 5 mg/ml
Nanosphere

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
solvent: Aqueous dispersion concentration: 5 mg/ml
Scanning Electron Microscopy (SEM)
18035858
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 2 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanotube Trigger=solvent: Aqueous dispersion concentration: 2 mg/ml
Nanotube

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
solvent: Aqueous dispersion concentration: 2 mg/ml
Scanning Electron Microscopy (SEM)
18035858
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 3 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanosphere spherical structures Trigger=pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 1mg/ml (1st dipeptide) + 1mg/ml )2nd dipeptide
Nanosphere spherical structures

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 1mg/ml (1st dipeptide) + 1mg/ml )2nd dipeptide
Scanning Electron Microscopy (SEM), HR - SEM (High Resolution Scanning Electron Microscopy), Transmission Electron Microscopy (TEM), AFM (Atomic force Microscopy)
23061818
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 4 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanosphere Spherical structures Trigger=temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
Nanosphere Spherical structures

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
HR - SEM (High Resolution Scanning Electron Microscopy) and DLS (Dynamic light scattering)
25391268
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 5 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanofiber Fibril Nanostructure Trigger=temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
Nanofiber Fibril Nanostructure

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
HR - SEM (High Resolution Scanning Electron Microscopy) and DLS (Dynamic light scattering)
25391268
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 6 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanotube Trigger=temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
Nanotube

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
temperature: Room temperature solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml
HR - SEM (High Resolution Scanning Electron Microscopy) and DLS (Dynamic light scattering)
25391268
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 7 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanosphere Trigger=temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + Ethanol concentration: 5mg/ml
Nanosphere

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + Ethanol concentration: 5mg/ml
Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and AFM (Atomic Force Microscopy)
24301009
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 8 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanostructure nanovasicles Trigger=temperature: Room temperature solvent: 1,1,1,3,3,3-hexafluoro-2- propanol (HFIP), lyopHilized concentration: 3mg/ml
Nanostructure nanovasicles

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
temperature: Room temperature solvent: 1,1,1,3,3,3-hexafluoro-2- propanol (HFIP), lyopHilized concentration: 3mg/ml
SEM, HRTEM, AFM
29379926
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 9 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Trigger=temperature: 60−80 °C solvent: Ethyl acetate and petroleum ether
Hydrogel

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
temperature: 60−80 °C solvent: Ethyl acetate and petroleum ether
30753058
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 10 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanosphere Spheres, fibrils and tubes Trigger=solvent: Water
Nanosphere Spheres, fibrils and tubes

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
solvent: Water
Scanning Electron Microscopy (SEM)
27582363
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Evidence 11 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Spherical structures with branching fibers Trigger=pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 5mg/ml (1st dipeptide) + 2mg/ml )2nd dipeptide
Spherical structures with branching fibers

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 5mg/ml (1st dipeptide) + 2mg/ml )2nd dipeptide
Scanning Electron Microscopy (SEM), HR - SEM (High Resolution Scanning Electron Microscopy), Transmission Electron Microscopy (TEM), AFM (Atomic force Microscopy)
23061818
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1301 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Evidence 12 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Necklaces like Nanostructue Trigger=pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 3mg/ml (1st dipeptide) + 3mg/ml )2nd dipeptide
Necklaces like Nanostructue

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 3mg/ml (1st dipeptide) + 3mg/ml )2nd dipeptide
Scanning Electron Microscopy (SEM), HR - SEM (High Resolution Scanning Electron Microscopy), Transmission Electron Microscopy (TEM), AFM (Atomic force Microscopy)
23061818
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1304 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Evidence 13 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Necklaces like Nanostructue Trigger=temperature: Room temperature solvent: HFP+50 % Ethanol concentration: 5mg/ml (1st dipeptide) and 3mg/ml (2nd dipeptide)
Necklaces like Nanostructue

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

N-terminal: Boc (or t-butoxycarbonyl)
temperature: Room temperature solvent: HFP+50 % Ethanol concentration: 5mg/ml (1st dipeptide) and 3mg/ml (2nd dipeptide)
Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and AFM (Atomic Force Microscopy)
24301009
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID 1453 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row.
Additional Detail Fields 5 fields
solvent: Aqueous dispersion concentration: 5 mg/ml concentration: 2 mg/ml pH: ~ 4.5 temperature: Room temperature solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl concentration: 1mg/ml (1st dipeptide) + 1mg/ml )2nd dipeptide solvent: 10% ethanol in water concentration: 0.2 - 10mg/ml solvent: HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + Ethanol concentration: 5mg/ml solvent: 1,1,1,3,3,3-hexafluoro-2- propanol (HFIP), lyopHilized concentration: 3mg/ml temperature: 60−80 °C solvent: Ethyl acetate and petroleum ether solvent: Water concentration: 5mg/ml (1st dipeptide) + 2mg/ml )2nd dipeptide concentration: 3mg/ml (1st dipeptide) + 3mg/ml )2nd dipeptide solvent: HFP+50 % Ethanol concentration: 5mg/ml (1st dipeptide) and 3mg/ml (2nd dipeptide)
N-terminal: Boc (or t-butoxycarbonyl)
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database. SAPdb ID 1301 nanostr_class=Other but nanostr gives explicit morphology low-detail seed row. SAPdb ID 1304 SAPdb ID 1453
18035858 23061818 25391268 24301009 29379926 30753058 27582363
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly