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Peptide record

TPDB87432

RADA16-KLT Selfassembly modified_plain modified
31 amino acids
Basic Information
TPDB87432
RADA16-KLT
Selfassembly
Self-assembling and biomaterial peptides
PMC
modified_plain
Yes
A 31-aa modified selfassembly peptide sequence curated from PMC, without an available 3D structural model.
C-terminal: Amidation
Sequence
Ac-RADARADARADARADA-KLTWQELYQLKYKGI-CONH2
Physicochemical Analysis
C175H279N57O53S2
MFPSV
A
4093.61
8.96
8
5
16
+2
8.11
-0.693
60.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
8605
210.21
8
Residue Composition
number
9
A
4
R
1
N
4
D
2
C
1
E
2
Q
1
G
1
H
1
I
3
L
3
K
0
M
0
F
0
P
0
S
1
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 9 R: 4 N: 1 D: 4 C: 2 E: 1 Q: 2 G: 1 H: 1 I: 1 L: 3 K: 3 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 2 V: 0
Chemical Descriptors
31
C175H279N57O53S2
4093.61
8.96
+2
8.11
-0.693
Self-Assembly Information 1 records
Record 1 PMC

Source

10.3390/gels6040061
Self-Assembling Peptide-Based Hydrogels in Angiogenesis

Self-Assembly

Nanostructure formation
Functionalized RADA16 nanofiber hydrogel
Physiological pH or salt
Selfassembly; Nanostructure=Functionalized RADA16 nanofiber hydrogel; Trigger=Physiological pH or salt
Angiogenesis review table reports RADA-I-KLTWQELYQLKYKGI
Angiogenesis ischemic tissue repair
tissue engineering scaffold
PMC
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Functionalized RADA16 nanofiber hydrogel Trigger=Physiological pH or salt
Functionalized RADA16 nanofiber hydrogel

Source & Reference

NA
PMC
10.3390/gels6040061

Other

N-terminal acetylation C-terminal amidation VEGF-mimetic KLT motif
Angiogenesis ischemic tissue repair
tissue engineering scaffold
Physiological pH or salt
Angiogenesis review table reports RADA-I-KLTWQELYQLKYKGI
Self-Assembling Peptide-Based Hydrogels in Angiogenesis
KLT motif is VEGF-mimetic proangiogenic sequence.
Additional Detail Fields 6 fields
Physiological pH or salt
N-terminal acetylation C-terminal amidation VEGF-mimetic KLT motif
KLT motif is VEGF-mimetic proangiogenic sequence.
Self-Assembling Peptide-Based Hydrogels in Angiogenesis
Angiogenesis ischemic tissue repair
tissue engineering scaffold