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Peptide record

TPDB87431

RADA16-PRG Selfassembly modified_plain modified
28 amino acids
Basic Information
TPDB87431
RADA16-PRG
Selfassembly
Self-assembling and biomaterial peptides
MDPI
modified_plain
Yes
A 28-aa modified selfassembly peptide sequence curated from MDPI, without an available 3D structural model.
C-terminal: Amidation
Sequence
Ac-RADARADARADARADA-PRGDSGYRGDSG-CONH2
Physicochemical Analysis
C131H210N54O50S2
EQILKMFTWV
A
3405.56
7.01
7
6
10
+0
11.42
-1.042
23.68
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1615
47.42
6
Residue Composition
number
9
A
6
R
1
N
6
D
2
C
0
E
0
Q
4
G
1
H
0
I
0
L
0
K
0
M
0
F
1
P
2
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 9 R: 6 N: 1 D: 6 C: 2 E: 0 Q: 0 G: 4 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
28
C131H210N54O50S2
3405.56
7.01
+0
11.42
-1.042
Self-Assembly Information 1 records
Record 1 MDPI

Source

10.3390/polym14235221
Modification Strategies for Ionic Complementary Self-Assembling Peptides: Taking RADA16-I as an Example

Self-Assembly

Nanostructure formation
Functionalized RADA16 nanofiber hydrogel
Physiological pH or salt
Selfassembly; Nanostructure=Functionalized RADA16 nanofiber hydrogel; Trigger=Physiological pH or salt
Review reports PRG-functionalized RADA16 promotes osteoblast adhesion/proliferation
Bone tissue engineering osteoblast adhesion
tissue engineering scaffold
MDPI
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Functionalized RADA16 nanofiber hydrogel Trigger=Physiological pH or salt
Functionalized RADA16 nanofiber hydrogel

Source & Reference

NA
MDPI
10.3390/polym14235221

Other

N-terminal acetylation C-terminal amidation PRG motif
Bone tissue engineering osteoblast adhesion
tissue engineering scaffold
Physiological pH or salt
Review reports PRG-functionalized RADA16 promotes osteoblast adhesion/proliferation
Modification Strategies for Ionic Complementary Self-Assembling Peptides: Taking RADA16-I as an Example
Sequence follows RADA16-I plus PRGDSGYRGDSG motif.
Additional Detail Fields 6 fields
Physiological pH or salt
N-terminal acetylation C-terminal amidation PRG motif
Sequence follows RADA16-I plus PRGDSGYRGDSG motif.
Modification Strategies for Ionic Complementary Self-Assembling Peptides: Taking RADA16-I as an Example
Bone tissue engineering osteoblast adhesion
tissue engineering scaffold